BME250: Molecular Biomechanics

Considers how assemblies of macromolecules (molecular motors) convert chemical energy into mechanical work on the nanometer-to-Angstrom scale. Processes examined in the course include ATP-dependent movement of organelles in the cytocsol facilitated by kinesin; proton pumping by ATPases in the mitochondrial membrane; viral genome packaging; bacterial movement driven by flagella; processive addition of nucleotides by polymerases during replication and transcription; and protein synthesis by ribosomes. Cannot receive credit for this course and course 150. Enrollment restricted to graduate students. Concurrent enrollment in course 250L required. M. Akeson

5 Credits

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