Computational Biology Tools

Computational Biology Tools: BME110 / BIOL181 

This course provides an introduction to sequence informatics and workflows relevant to high-throughput computational genomics.  

In addition to introducing core topics of sequence alignment and database mining (historically, central to BME110), the curriculum this quarter is designed to give students experience with advanced topics and applications of next-generational sequencing technologies. Biological concepts and online tools presented in this course are expected to be highly valuable to any student interested in developing skills expected of contemporary computational biologists.  


No prior experience with scripting languages or knowledge of unix environment is required.  Class problem sets will utilize the Galaxy web-based platform ( -- an online analysis framework common to life science research --  to analyze and integrate publicly available software and genomic datasets.  Additionally, the use of Galaxy is intended to introduce the importance of reproducibility and transparency in data management through the use of published workflows.

Instructors and Assistants